Sticking it to Cancer: How Molecular Glues Could Transform Treatment
Imagine a therapy that forces rogue cancer-causing proteins to self-destruct. Molecular glues offer just that — a ground-breaking avenue in targeted protein degradation, especially when conventional cancer drugs fail. By Neelabh Datta.
These small molecules foster binding interactions between harmful proteins and degradation signallers known as E3 ubiquitin ligases - these